Everything you need to know ahead of Los Blancos' La Liga clash in Andalusia on Saturday...
Real Madrid can take another step towards a first league title since 2011-12 by beating Granada in the Primera Division on Saturday night.
Zinedine Zidane's side dropped to second place in the table after losing the Clasico to Barcelona last month, but Los Blancos still have a game in hand over their fierce rivals.
Barca are at home to Villarreal on Saturday evening, with Madrid in action straight afterwards in Granada. The Catalans have just three games left including that one, with four still to play for Real.
Gareth Bale is still sidelined with a calf problem, while Dani Carvajal is also out after suffering a hamstring injury in the 3-0 win over Atletico Madrid in the Champions League on Tuesday night.
Raphael Varane has had a setback and will play no part against Granada, while Pepe is back in training but not quite ready to return for the weekend match.
Cristiano Ronaldo, Carvajal and Isco are all just one yellow card away from a ban, but the Portuguese is set to be rested for the Champions League anyway and the Spain defender is out injured.
With a tough game against Sevilla ahead next weekend, Zidane may also decide to keep Isco in reserve to avoid a booking that would see him miss that match.
With the Champions League semi-final second leg against Atletico coming up on Wednesday, Zidane will keep most of his first-choice players in reserve for Saturday's match in Granada.
Ronaldo and Karim Benzema are set to be rested, along with Casemiro, Isco, Luka Modric and Marcelo.
Kiko Casilla could also come in to give Keylor Navas a breather, but Sergio Ramos will be needed because Pepe and Varane are unavailable.
Granada have already been relegated after four consecutive defeats under interim coach Tony Adams and will be playing for nothing more than pride (and to avoid finishing bottom) in this match.
The Andalusian side are down in 19th place, just one point above Osasuna with three matches left to play.
Adrian Ramos, Dimitri Foulquier and Gaston Silva are all set to miss the game against Madrid through injury, while Matthieu Saunier, Artem Kravets and Hector Hernandez are doubtful after all three were absent in the defeat at Real Sociedad at the weekend.
Barcelona loanee Sergi Samper is also unlikely to feature again as the club look to save funds ahead of their return to the Segunda Division and are paying the Catalan club more money every time the midfielder appears in the first team.
Granada versus Real Madrid kicks off at 20:45 CEST and will be shown live from 19:30 UK time on Sky Sports 5 straight after Barcelona's game against Villarreal on the same channel.